pe 22 28 (10mg)
pe 22 28 (10mg)
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3rd party lab tested
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PE-22-28 (10mg)

$ 45

PE-22-28 – Research Peptide
PE-22-28 is a synthetic derivative of spadin, a peptide derived from sortilin, studied for its potential role as an antagonist of the TREK-1 (TWIK-related potassium) channel. TREK-1 modulation is of significant interest in neurological research, particularly in models of depression, neurogenesis, and cognitive function.

Preclinical studies indicate that PE-22-28 may enhance neurogenesis and synaptogenesis in the hippocampus, potentially promoting neuronal growth, synaptic connectivity, and mood stabilization. The peptide has been reported to exhibit enhanced stability and rapid onset of action compared to native spadin, positioning it as a promising tool in research on depressive disorders, post-stroke depression, and nootropic effects.

Mechanism of Action:
PE-22-28 is believed to act as a TREK-1 receptor antagonist, modulating potassium ion flow in neurons and influencing neurotransmitter release. This inhibition may enhance neurogenic responses and support synaptic formation, contributing to its observed effects on mood and cognitive models.

1-2 Business Days Shipping
Categories: , Product ID: 8612

Description

Product Information:

  • Peptide: PE-22-28
  • Purity: >98%
  • Form: Lyophilized powder
  • Content: 5mg per vial
  • Storage:
    • Unreconstituted: Store at -20°C (-4°F)
    • After reconstitution: Refrigerate at 2–8°C (36–46°F); use within 30 days
  • Grade: For research use only

Common Research Applications:

  • Depression and post-stroke depression studies
  • Hippocampal neurogenesis and synaptogenesis research
  • Nootropic and cognitive function investigations
  • TREK-1 modulation and neuronal signaling studies
  • Exploratory studies on muscle function and neuroprotection

Disclaimer:
This compound is intended for laboratory research only.
It is not approved for human use.
SOLD FOR RESEARCH PURPOSES ONLY.

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I have been ordering with Truelab for some time now. Great products and great customer service
Kevin Diaz

United States

Got tracking within an hour of purchase and my package arrived before the weekend, ready for my reaserch project
Angelika

Canada

Spoke with Robert who was very attentive and helpful. Ordered GHk-cu and it was delivered in 3 days. Great communication and will be ordering again
Ana

United States

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I understand these products are for research use only and not for use in people or pets. I am purchasing these items for laboratory or research purposes only. They are not for human or animal use, not medicine, and not for diagnosing, treating, or curing any condition. I will follow all applicable laws and safe handling rules. I accept that this website, and our affiliates, are not responsible for how I use or store these items once delivered, to the fullest extent allowed by law. In accordance with industry guidelines, access to this website is restricted to individuals 21 years of age or older. This site provides information and products strictly for laboratory and research use. Are you over 21 years of age?

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Disclaimer: Peptides: This product is intended for laboratory research use only and is not approved for human consumption, medical, or veterinary use. Peptides are sold solely for research and development purposes by qualified professionals. Buyers are responsible for handling all materials in accordance with local regulations and safety guidelines. Waave Compliance blocks all international shipping.